There is good news for Lyon, as Nabil Fekir is ready to start. According to the Uefa chart, which may not be entirely accurate, the hosts will play with three on the back and two sides, which would be a radical change from the 4-4-1-1 they used with both success against Man City in Etihad. Moussa Dembele is out and does not even make the Lyon bench.
Phil Foden does not start for City, with Fernandinho, Riyad Mahrez and David Silva taking the midfield. John Stones returns to Nicolas Otamendi, Oleksandr Zinchenko replaces Fabian Delph and Riyad Mahrez is for Ilkay Gundogan.
Lyon: Lopes, Denayer, Marcelo, Marcal, Da Silva, Ndombele, Aouar, Mendy, Bugle, Depay, Fekir.
Subs: Gorgelin, Terrier, Traore, Morel, Tete, Cheikh, Tousart.
City of Man: Ederson, Walker, Stones, Laporte, Zinchenko, Mahrez, Fernandinho, Silva, Sane, Aguero, Sterling.
Subs: Muric, Danilo, Kompany, Delph, Otamendi, Foden, Diaz.
Judge: Gianluca Rocchi (Italy)