Award from the Grünenthal Foundation for Clinical Research. Collect the award Javier Muriel, Domingo Morales and Ana María Peiró
The prize in the category of Preclinical Research was granted to a work that deepens the knowledge of the mechanisms of generation of neuropathic pain.
The University of Salamanca hosted the delivery of the 19th edition of the Doré & # 39; attributed by the Extraordinary Pain Chair of the Grünenthal Foundation and the Salamanca Study. This award convened annually to recognize and promote the most innovative projects on the knowledge of pain in the field epidemiological, experimental, pharmacological and clinical.
Prize in Preclinical Research
The prize in the pre-clinical research category was awarded to Enrique J. Cobos, Department of Pharmacology and Institute of Neurosciences, Faculty of Medicine, University of Granada for his work entitled "Mechanistic differences in neuropathic pain modalities revealed by the correlation of behavior with the overall expression profile." The work published in the journal Mobile reports and conducted jointly by the University of Granada, Harvard University, University of California at Los Angeles (UCLA), Université Laval and The Jackson Laboratory, analyzes the profile of genetic changes that occur after a nerve injury to deepen the knowledge of the mechanisms of generation of neuropathic pain, caused by injuries to the nervous system.
In neuropathic pain, normal touch or temperature sensory stimuli they are interpreted by our nervous system as if they were very painful sensations. This anomalous response is called allodynia.
As detailed by the winner, Enrique J. Cobos, "With this approach, we show that while cold allodynia is produced by neuronal changes in direct response to nerve damage, the origin of allodynia to touch is very different, being the result of a complex process in which the interaction between the system participates. immune system and nervous system ".