Aspirin, used in low doses, could reduce the severity of the symptoms and abnormalities in the immune system of patients with multiple sclerosis, after having proven effective in an experiment with mice, according to a study published today in the journal. Scientific Signaling.
According to the research, orally administered aspirin in laboratory mice reduced the severity of symptoms, slowed myelin degradation and inhibited the infiltration of cells into the spinal cord.
The amount of aspirin applied to rats was equivalent to one dose of the infant version of the drug in adult humans.
Multiple sclerosis is a degenerative disease that affects more than 2.3 million people worldwide and whose origin is the loss of myelin, a protein of the nervous system responsible for the transmission of electrical impulses and to protect the neurons.
Researchers at Rush University (Chicago) have discovered an unknown effect of this common drug, commonly used to relieve pain.
With a small amount, aspirin was able to stimulate the production of nerve-positive cells, while decreasing the activity of malignant cells – Tregg – that attack the nervous system, degrade the mile and are responsible for the imbalance which causes the symptoms of multiple sclerosis.
The scientific team, led by Susanta Mondal, pointed to safety of the active principle of aspirin and its ease of administration, so that it could be reused as supportive therapy for patients with multiple sclerosis and other autoimmune disorders associated with the disease. dysfunction of the same Treg cells. EFE