David Leitch, whose credits include "Deadpool 2" and "Hobbs & Shaw", is directing the project, which was announced at E3 at the Los Angeles Convention Center. Rafe Judkins is adapting the script.
The story is set in the near future with a pandemic virus strewn with paper money on Black Friday, decimating New York City and killing millions of people. At Christmas, what remains of society has descended into chaos. A group of civilians, trained to operate in catastrophic times, are activated in an attempt to save who and what is left.
87North Productions, Gineenhaal's Nine Stories, Chastain's Freckle Films and Ubisoft Film and Television are producing the film.
"Tom Clancy's The Division" has become the best selling videogame in history and currently has more than 20 million players. A sequel released in March.
Chastain was nominated for an Oscar for "Zero Dark Thirty" and "The Help". His other credits include "Molly's Game," "The Martian," "A Most Violent Year," and "The Zookeeper's Wife." She can currently be seen in "Dark Phoenix" and will appear in "It: Chapter 2."
Gyllenhaal received an Oscar nomination for "Brokeback Mountain" and also appeared in "Nightcrawler", "Nocturnal Animals" and "Stronger."