We all know that exercise has many benefits of helping to treat high blood pressure to protect against Alzheimer's disease. Now, a new study is revealing that the time of day that the workouts take place could play a key role for patients with metabolic disorders.
Researchers at the University of California, Irvine, found that exercise in the morning, not at night, offered metabolic benefits.
"Using mice, we compared the impact of exercise on skeletal muscle metabolism at different times of the day," said Paolo Sassone-Corsi, PhD, Professor Donald Bren and director of the Center for Epigenetics and Metabolism at the UCI School of Medicine.
"We found that exercise at the right time of the day – around mid-morning – results in more oxygen in the cells and a more rejuvenating effect on the body."
It was well known that food intake time played a crucial role in moderating metabolism, but the effect of exercise time has remained a mystery so far.
"Exercise stimulates metabolism, leading to improved metabolic health." While the metabolic benefits of exercise have been widely discovered, the question of when it is appropriate for exercise has remained largely unexplored, "said Sassone-Corsi.
The team explored transcriptomic and high-throughput metabolic approaches to identify changes in the metabolism of mice that occurred during morning or night exercises. They found that morning impact exercise exhibited increased use of carbohydrates and ketone bodies, as well as breaking down fats and amino acids.
"Our results clearly indicate that time of day is a critical factor in amplifying the beneficial impact of exercise on both metabolic pathways in skeletal muscle and systemic energy homeostasis," said Sassone-Corsi.
Will you be changing your workouts in the morning?
This study is published in Cellular Metabolism.