A University of Washington study showed that women's brains were about three years younger than men's, and offer a clue as to why women tend to stay mentally sharper longer than men.
In a study published Monday in the Proceedings of the National Academy of Sciences, researchers studied 205 people to find out how their brains use a portion of sugar in a process called aerobic glycolysis that kept the development of the brain but decreased with age. .
They examined brains of 121 women and 84 men aged 20 to 82 years to measure the flow of oxygen and glucose in their brains and determine the fraction of sugar used for aerobic glycolysis in various regions of the brain.
They used an artificial intelligence algorithm to find a relationship between age and brain metabolism, fueling the ages of men and brain metabolism data.
The researchers then added data on women's brain metabolism to the algorithm and directed the program to calculate the age of each woman's brain from their metabolism.
According to the study, the algorithm produced a mean brain age of 3.8 years younger than the chronological age of women.
On the other hand, they trained the algorithm on women's data and applied it to men. The findings are that the brains of men were 2.4 years older than their actual ages.
In addition, the relative youth of women's brains were detectable even among the younger participants, over 20 years of age.
"We are beginning to understand how various factors related to sex can affect the path of aging in the brain and how this may influence the vulnerability of the brain to neurodegenerative diseases," said lead author Manu Goyal, assistant professor of radiology at the University