Association between BMI and mortality from pancreatic cancer


Eric J. Jacobs, PhD, a cancer epidemiologist and strategic director of pharmacoepidemiology at the American Cancer Society, discusses the results of a prospective cohort study that examined the association between BMI and mortality from pancreatic cancer.

Those included in the survey did not have cancer before the study began, says Jacobs, who recorded 967,317 American adults between 30 and 89 years of age. The results of the study were presented at the Annual Meeting of the AACR in 2019 and showed that excess body weight at any age was associated with an increased risk of fatal pancreatic cancer. However, it is important to note that the increase in risk for weight measured in someone's 30 or 40 years was substantially greater than in someone who was measured in their 70s or 80s, says Jacobs.

Researchers found that in those who reported their weight when they were in their 30s or 40s, for every 5 BMI units (about 30 or 35 pounds), there was a 25% increase in the risk of pancreatic mortality for the rest of their lives . front. When researchers looked at those between the ages of 70 and 80, they still saw increased risk, but it was only about half of that, showing a clear trend. These findings mean that it's important when overweight is measured in life, and being overweight in someone in their 30s or 40s can be incredibly important to weight gain later in life, concludes Jacobs.

<<< 2019 AACR Annual Meeting


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