Monday , October 18 2021

Prevention of early bowel cancer in intestinal bacteria



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Research team day

[의학신문·일간보사=정우용 기자] Techniques have been developed to detect early colon cancer from the type of intestinal bacteria in the intestine.

A team of researchers at the University of Osaka and Tokyo Tech in Japan have managed to find about 80% accuracy and expect it to be used for early detection and treatment as a hepatotoxic test that replaces the occult blood test. The results of the research were published in Nature Medicine.

The liver cancer liver transplant test is a common antebrachial test to examine blood mixed with feces. However, the proportion of cancer patients who are positive to diagnose hemorrhoids as cancer patients is only 5%.

In addition to healthy individuals, the team collected a total of 600 stools, including benign polyps, or patients with advanced and worsened colon cancer, and examined the types of intestinal bacteria by genetic analysis. We investigated the increase of germs in patients with gynecological cancer and the reduction of germs in patients with gynecological cancer, and by combining them, we were able to distinguish healthy and early or worsening cancer patients with about 80% accuracy. So far, it has been difficult to distinguish patients from those who became familiar with the types of germs that are increasing in exacerbated cancers.

Based on these data, the researchers developed an artificial intelligence (AI) that distinguishes patients. We plan to test the performance of the testing technology on a large number of patients and healthy people in the future and develop a test kit after five years.

Reporter Jung Woo-yong [email protected]

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