NK cells in diabetics, only 30% of normal people


People with diabetes may have less immunity and other diseases may be more likely to occur, the research shows.

Ahn Chul Woo, Nam Ji Sun, Kim Jung Hye, professor of endocrinology, Gangnam Severance Hospital, investigated the activity of NK (Natural Killer) cells, which is responsible for the immunity of our body, and confirmed the decreased immunity of patients with diabetes type 2 (adult diabetes) 17 days ago.

Gangnam Internal Medicine Hospital of Endocrinology Ahn Chul Woo, Nam Ji Sun, Professor Kim Jung Hye (left)

The researchers measured the activity of NK cells in the blood in 13 normal blood glucose groups, 15 pre-diabetics and 21 diabetics. As a result, the NK cell activity of diabetic patients was 768.01, significantly lower than that of the normal glycemic group (2435.31) and the pre – diabetic group (2396.08). There was no significant difference between the normal glycemic group and the pre – diabetic group.

Diabetes is a hormone that lowers blood sugar, insulin-like type 1 diabetes, and insulin is usually secreted, but insulin resistance due to insulin does not work because type 2 diabetes is divided into. Type 2 diabetes is responsible for the majority (more than 90%).

Chronic vascular injury can lead to various complications such as the cardiovascular, renal, retinal and peripheral nerves, and the disturbance of the immune system has also been pointed out as a complication. But this is the first time that a study has shown how much of the immune system's diabetes is suffering, according to the researchers.

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Professor Ahn Chul-woo said: "If immunity is weak, it is likely to be accompanied by infectious diseases such as colds and pneumonia or cancer and other diseases that are fatal to the human body." Decreased immunity of diabetic patients is caused by diabetic retinopathy, kidney disease, atherosclerosis. More research is needed to see if it affects the "If we increase patient immunity, we can reduce the complications of diabetes and its future mortality rate."

The results of this study are as follows: <당뇨병연구저널>In a recent issue of the Journal of Diabetes Investigation.


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