A new study has raised questions about the long-term effectiveness of the pertussis vaccine given to children.
Published in Pediatrics on June 10, suggests that the efficacy of the vaccine, commonly known as DTaP, could be reducing or failing to achieve desirable results as the child grows.
The study found that the risk of pertussis infection was 13 times higher among children who are not vaccinated and 1.9 times higher in children who were sub-vaccinated compared to fully vaccinated children.
In addition, the results also showed that among children who were adequately vaccinated, the risk of pertussis increased as they moved away from the last dose of DTaP.
"This suggests that vaccine efficacy decreases over time," said Ousseny Zerbo, a team scientist at the Vaccine Study Center in Northern California.
The study enrolled 469,982 children ages 3 to 11 from northern California in the United States, where 738 cases of pertussis were identified.
Of the 738 cases, 99 were not vaccinated, 36 were sub-vaccinated, 515 were fully vaccinated and 88 were fully vaccinated plus one dose.
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Vaccine against convulsive coughType of weaningDTaP