Treating Cancer with Immunotherapy | Republika Online


The principle of immunotherapy uses the immune mechanism of the body's own cells versus cancer

REPUBLIKA.CO.ID, JAKARTA – Immunotherapy is the latest advancement in cancer treatment. This therapy uses the body's immune system to fight cancer cells and this is not only applicable to patients with lung cancer.

Consultant in Medical Hematology and Oncology, MRCCC Siloam Hospitals, dr. Jeffry B. Tenggara, Sp.PD, KHOM, said the cancer is growing slowly, and at first the human immune system can eradicate cancer cells before it develops further. Over time, cancer cells grow faster, so the immune system can no longer compensate for cancer growth. Some cancers also have mechanisms to destroy T lymphocytes.

"So the principle of immunotherapy is to use the immune mechanism of our own body cells to fight cancer," said Dr. Jeffry

Immunotherapy is now widely used checkpoint inhibitor one of which is anti-PD 1. In Indonesia, the anti-PD-1 is approved by the Food and Drug Administration (BPOM) for the treatment of lung cancer and malignant melanoma. This is the most malignant type of skin cancer that affects Jimmy Carter.

Now its use is not limited to the two types of cancer. In research and practice, anti-PD-1 immunotherapy is also used for several other cancers, which have been shown to express PD-L1.

Medical oncologist Dr. dr. Andhika Rachman, Sp.PD-KHOM of FKUI / RSCM, Jakarta, Indonesia, used this drug for patients with pancreatic cancer, breast cancer, gall bladder cancer for head and neck cancer. Anti-PD-1 is generally given to patients with poor physical performance.

"Drugs administered for systemic therapy should not reduce the patient's performance status," he said.

The results are very good with no side effects, although the effectiveness is not as good as in lung cancer and melanoma. The oldest patient who received anti-PD-1 immunotherapy by Dr. dr. Andhika is 82 years old, suffers from pancreatic cancer. The patient received 12 PD anti-PD. This patient is still alive today, more than a year after treatment with anti-PD 1.

"Even during treatment, the quality of life is good. It can perform daily activities as usual," he continued.


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