Washington D.C., June 20: Researchers have developed a new blood test called a biomarker test that offers the possibility of more accurate diagnoses of ovarian cancer without the need for surgery.
The biomarkers test is based on the analysis of 11 proteins and is performed on a blood sample in which ultrasound indicates abnormalities to identify women without cancer.
As most women who undergo surgery for suspected ovarian cancer do not have cancer, this research could lead to a reduction in unnecessary surgery and early detection and treatment for the affected women.
Ovarian cancer is often discovered at a late stage and has a high mortality rate. Of the 10 patients, only 3-4 survived 5 years after treatment, and there was no specific test sufficient to justify screening, the study reported in the Journal of Communications Biology.
Women with accidental findings of an ovarian cyst or with symptoms undergo ultrasound, and if abnormalities are observed, surgery is the only way to ensure that all cancers are detected. This means that many women are operated on without cancer, resulting in unnecessary surgeries and increased risk for women.
"We need to develop more accurate preoperative diagnoses.To detect a cancer, we operate with up to five women – however, this is currently the best option when abnormalities are detected by ultrasonography and suspected cancer. simple blood that could identify women who do not need surgery, "said one of the researchers, Karin Sundfeldt.
For cases where doctors chose to operate, the rate of cancer could increase by one in five to one in three. This would greatly reduce unnecessary surgery and the risk of complications related to surgery.
The biomarker profile can also detect borderline cases and early stages of the disease.
"Our results are promising enough to consider screening for the early discovery of ovarian cancer." In Sweden, we have a long track record of cervical cancer screening, and I see great prospects for developing a strategy for screening for cancer of the uterus. ovary, which can save lives and minimize the need for surgery to rule out cancer, "said Ulf Gyllensten, another study investigator.