Johns Hopkins first to transplant the HIV-positive donor kidney to HIV receptor


For the first time, a team from Johns Hopkins Hospital in Baltimore transplanted a kidney from a person living with HIV to a transplant recipient who is also living with HIV. Doctors say both the donor and recipient are well, according to a Johns Hopkins press release.

"This is the first time anyone living with HIV is allowed to donate a kidney, in the world, and that is huge" Dorry Segev, MD, PhD, professor of surgery at Johns Hopkins University School of Medicine, said in the statement. "An illness that was a death sentence in the 1980s has become so well controlled that those living with HIV can now save lives by donating kidneys – that's incredible."

People living with HIV have not been able to donate the kidneys so far because there were concerns that HIV was a very high risk factor for kidney disease in the donor, according to the statement. However, recent research by Segev and colleagues about more than 40,000 people living with HIV have shown that new antiretroviral drugs are safe for the kidneys and that those with well-controlled HIV have basically the same risks as those without HIV and are healthy Enough to donate kidneys.

"What is significant about the first living kidney donor – who also lives with HIV – is that it advances medicine at the same time that it defeats the stigma. This challenges providers and the public to see HIV differently, " Christine Durand, MD, associate professor of medicine and oncology and a member of the Comprehensive Cancer Center Johns Hopkins Sidney Kimmel said at the launch. "As patients waiting for a transplant see that we are working with as many donors as possible to save as many lives as possible, we are giving them hope." Every successful transplant shortens the waiting list for all patients regardless of your HIV status. "

Doctors will continue to closely monitor the recipient and the donor. In light of the new predictive factors and highly effective antiretroviral therapy options available, the team says it is optimistic that long-term HIV control and kidney function will be excellent, according to the publication.


Disclosure: The work is supported by the National Cancer Institute, National Institutes of Allergy and Infectious Diseases, NIH, CDC and Agency for Research and Quality in Medical Care (NCT02602262).


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