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A sugary substance in cranberries can help fight cancer cells



BBC



Posted in:
Thursday, November 22, 2018 – 13:29
| Last update:
Thursday, November 22, 2018 – 13:29

Researchers have been able to slow the development of some types of cancer cells in mice and increase the effect of treatments used to eliminate the disease using a dietary supplement of diabetes found in some fruits.

The researchers conducted a study on mice with pancreatic, lung or skin cancer using mannose dietary supplement, a sugar compound found in cranberries and other fruits.

The researchers found that the substance slowed the growth of cancerous tumors significantly without the presence of clear side effects in rats.

However, cancer patients have been warned against using mannose supplement because of the risk of its side effects in humans.

Scientists hope the food supplement will soon be tested on humans.

Scientists believe that maneuver affects the ability of cancer cells to use glucose in the body to grow and spread, and can be obtained from health food stores and is sometimes used to treat urinary tract infections.

"Perfect balance"
The researchers also looked at how Manoz had influenced cancer drugs and gave them to mice that had already received two of the drugs most commonly used in chemotherapy – cisplatin and doxorubicin.

The result was that it helped increase the effect of chemotherapy and thus decreased the growth of tumor tumors and decreased their size. It also increased the lives of some rats with cancer.

Different cancer cells have also been exposed to the manus effect in the laboratory, including cancers of the blood, bone, ovaries and intestines.

Some cells responded well, but some did not.

The response of cancer cells depends mainly on the presence of levels of the enzyme that helps break down the mannose supplement.

Professor Kevin Ryan of the Bateson Research Institute in Britain said his team found that a dose of manganese supplement could "block the intake of glucose enough for cancer cells and slow the growth of the tumor in mice but would not affect tissues normal ".

Objects need glucose for energy, but cancerous tumors also use them to feed, grow, and spread.

"Research is still early, but finding that perfect balance means that in the future, manoeuvering can be given to cancer patients to promote chemotherapy without undermining their overall health," Ryan said.

Additional notice
One of the main advantages of handling food supplements is the cheap price compared to medicines produced by pharmaceutical companies.

Professor Ryan said he expects experiments on humans to begin soon.

"While these findings are very promising for the future of some cancer treatments, this research is very early and has not yet been tested in humans," said Martin Ledwick, chief of nursing at the British Center for Cancer Research.

He cautioned that patients should not use mannose on their own because there is a real risk of adverse side effects that have not yet been tested.

"It's important to see a doctor before you drastically change your diet or take new supplements."

Professor Ryan said his team would study why Manoz worked with some cancer cells alone so they could identify the patients who would benefit most.

The study was published in the journal Nature.


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