Sunday , March 7 2021

The cocktail that inspired a group of Chinese researchers to create a contraceptive for men | Photo 1 of 6 | Science



O male contraception It has a promising future. Several methods are going through the early stages of successful clinical trials in order to reduce the weight of contraception in women.

Along these lines, a group of Chinese researchers found inspiration for a new method of male contraception, nothing more and nothing less than a multicolored cocktail called galaxy.

It turns out that this is a combined alcoholic whose components form colored layers in the glass in which it is prepared, which resembles a galaxy in space. The researchers noted that this drink formed perfectly separated layers. However, when stirred or subjected to heat, the layers broke and the components were mixed in one.

Thus was born the idea of ​​a contraceptive that functions in the same way as the cocktail, but within the vas deferens, which are the channels through which the semen is transported from the testicles to the urethra.

As detailed in the article published in ACS Nano , the results obtained by the team of Xiaolei Wang were positive in their tests in rats. Thus, they created a contraceptive whose effect could be annulled with the heat.

HOW IT WORKS?

The researchers sequentially injected four layers of different substances into the deferent duct of male rats. The first layer consists of hydrogel, a substance that acts as a physical barrier to prevent the passage of sperm.

They then injected a layer of gold nanoparticles, which are heated radiating infrared light over them. They then injected the ethylenediaminetetraacetic acid (EDTA), which breaks the gel and kills the sperm and seals the duct with another layer of gold nanoparticles.

In this way, the sperm is not only prevented from advancing through the ducts, but they are eliminated by EDTA. But the interesting thing is that if you want to reverse the contraceptive process, just warm up with infrared and the gold nanoparticles will do their work, mixing with the rest of the layer and allowing the sperm to pass again.

Now that its effectiveness has been demonstrated in mice, researchers hope to test their method in humans as well as ensure the safety of the compounds used.


Source link