Scientists at King's College London have discovered that one of the causes of chronic fatigue syndrome (CFS) could be the Hyperactivity of the immune system.
According to a study published in the journal Psychoneuroendocrinology, today the syndrome itself and the factors that cause it are poorly understood. However, experts have long assumed that the disease not only has a psychological basis, since the symptoms of CFS often manifest in patients after a severe cold or as a result of viral infections.
The researchers found that this is possible in the case of an immune system prone to hyperreaction. Scientists believe that this factor is determined genetically.
To reach that conclusion, the researchers looked at 55 volunteers with hepatitis C who received a cycle of interferon alpha injections for 6 to 12 months, a protein that the body naturally produces and stimulates white blood cells to elicit an immune response. .
Most patients who recovered from hepatitis C experienced an increase in fatigue during treatment, which was reduced when injections were completed. However, 6 months after the end of treatment, 18 participants remained more fatigued than before starting treatment.
However, 6 months after stopping the injection, the results of the analysis did not show differences in IL10 and IL6 protein levels between patients with and without persistent fatigue.