It is difficult for skin burns to heal completely if they are large, if there are severe microbial infections or if patients have diabetes. Chronic wounds are very painful and expensive to treat, so there is a great demand for biomedical materials that help facilitate healing and are effective against infections.
Researchers at Jiaotong University in Xi'an, Shaanxi Province, northwest China, have designed a type of antibacterial biomimetic material that promotes skin regeneration.
The substance is elastic as skin and biocompatible, and can prevent bacterial infections resistant to multiple drugs. In experiments performed on mice, the material stimulates the healing and regeneration of appendages of the skin, such as hair follicles, and ultimately leads to tissue regeneration.
The research provides a new strategy for the design of biomedical materials for regenerative medicine.
The study was published in the journal ACS Nano.