Researchers at UNAM have discovered the effectiveness of Mexican arnica for colon cancer treatments



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The National Autonomous University of Mexico (UNAM) revealed that the researchers discovered that derived from Mexican arnica, plant with anti-inflammatory properties, they have a high toxic effect on colon cancer cells.

The research is led by Daniela Araiza, PhD in Biomedical Sciences of the Department of Biomacromolecules and Guillermo Delgado, Department of Natural Products, both of the Institute of Chemistry. They worked with molecules derived from Mexican arnica ("Heterotheca inuloides") and found that they have a toxic effect on cancer cells, the UNAM said at the time of the study. World Day Against Colon Cancer, which is celebrated on March 31.

"Taking into account that this disease can be promoted by chronic inflammation of the intestine, we look for molecules that prevent inflammation, " Araiza said in a statement released by UNAM.

The doctor explained that the aforementioned study analyzes the effect that these arnica derivatives have on a "transductional and metabolic level in rectal adenocarcinoma cells".

It is sought that these molecules "attack" the tumor cells, He explained detailing that current treatments with surgeries, radiation and chemotherapy have side effects, affecting healthy and cancerous cells.

This type of cancer is characterized by uncontrolled growth of cells anywhere in the colon or rectum, the doctor explained.

It may begin as a benign tumor called "adenomatous polyp" and become cancerous over time. Statistics of the Institute of Cancerology of Mexico and the Institute of Public Health indicate that 95% of these cancers begin in the mucus-producing glands which protects the inside of the colon and rectum, the so-called adenocarcinoma.

"It is not known with certainty what causes, but It is very much related to lifestyle, with genetic mutations or changes in metabolism, " explained Dr. Araiza.

Its symptoms are changes in defecation-diarrhea, constipation, thinnest stools, rectal bleeding, dark stools, cramps, abdominal pain, weakness and tiredness, persistent need to defecate.

Araiza said patients should be considered if they have inflammatory bowel diseases and family history and call people over the age of 50 who present these symptoms periodically.

"If patients are diagnosed early on, the recovery percentage is very high, "added the researcher.

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