Wednesday , April 21 2021

Researcher Urban Urban – UOH was awarded the Research Project of the Chilean Society of Endocrinology and Diabetes



In addition, Dr. Paulina Ormazábal, from the Institute of Health Sciences, presented some preliminary results corresponding to this new line of research at the XXIX SOCHED Congress, held in Coquimbo.

Dr. Paulina Ormazábal, an academic from the Health Sciences Institute (ICS), received funding from the Chilean Society of Endocrinology and Diabetes (SOCHED), which seeks to promote the development of basic epidemiological clinical, clinical or clinical research in Endocrinology and Diabetes, which can serve as the basis for more advanced lines of study or projects.

Dr. Ormazábal applied to the fund with his project "Effect of plant Lampaya Medicinalis Phil on the activation of JNK and the levels of TNF-α and FABP4 induced by fatty acids in human hepatocytes HEPG2, "which constitutes a new branch within the research that UOH academic develops on the beneficial effect of the endemic plant of the Chilean highlands, Lampaya Medicinalisagainst inflammation induced by fatty acids in hepatic cells.

"With these funds, I will be able to choose to evaluate new molecular markers of inflammation through much more specific and sensitive laboratory techniques," explained Dr. Ormazabal.

Regarding the importance of granting this fund, the researcher stated that "it is an acknowledgment of the research work that is developed within the UOH. This work aims to validate the ethno-pharmacological knowledge about the use of medicinal plants for the treatment of diseases. In particular, this study will study a phenomenon that frequently occurs in obesity and which corresponds to inflammation of the liver due to the accumulation of fats inside the hepatic cell. The above is transcendental when overweight and obesity are conditions with high national prevalence and globally and unfortunately our region does not escape this reality ".

The scientifically verify that the Lampaya Medicinalis It has an anti-inflammatory effect, will have great local and national impact, since it is a native Chilean plant, and can design its use as complementary therapy for the treatment of inflammatory liver phenomena associated with overweight and obesity.

Among the top five of the SOCHED Congress

In addition, Dr. Ormazábal presented the preliminary results corresponding to this new line of research at the XXIX SOCHED Congress, held in the municipality of Coquimbo, between November 8 and 10.

The title of the paper presented at the congress was "Effect of the hydroalcoholic extract of the Andean plant Lampaya in in vitro induced steatosis in human hepatocytes "

On the occasion, the work was selected among the top five in the area of ​​translational endocrinology.

This research is the product of the multidisciplinary work of chemists, biologists and biochemists. The extract of Lampaya Medicinalis It is prepared and donated by researchers from the Laboratory of Biological Chemistry of the Antofagasta Institute, University of Antofagasta, while the experiments are carried out in the Laboratory of Obesity, Metabolism and Aging of INTA.

It is worth mentioning that in October of this year, the ICS academic was awarded the SOCHINUT Award – Henri Nestlé Scientific Development Fund 2018, which seeks to provide support and visibility to researchers who, through their active and innovative work, contribute to the improvement of the quality of life of Chileans in the areas of food, nutrition and health – with their research project "Protective effect of Lampaya medicinal plant Phil. on steatosis and fatty liver-induced hepatic inflammation in human HEPG2 hepatocytes."

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