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Scientists synthesize molecule that eliminates hepatitis C virus – Jornal da Manhã



Scientists synthesize molecule that eliminates hepatitis C virus

According to the study, the compound attacks much more the virus than the host cell

17/11/2018 – 09:38:44. Last updated: 18/11/2018 – 10:15:46.

Photo / Sumaia Villela / Agência Brasil

According to the study, the compound attacks much more the virus than the host cell

Researchers at the Universidade Estadual Paulista (Unesp) have synthesized a new compound that inhibits the replication of the hepatitis C virus at various stages of its cycle. The study, carried out with the support of the Foundation for Research Support of the State of São Paulo (Fapesp), consisted of combining existing molecules to produce new biological compounds, a method called bioconjugation.

The new compound, called AG-hecate, is also capable of acting on bacteria, fungi and cancer cells.

According to one of the authors of the study, the chemist Paulo Ricardo da Silva Sanches, this type of action is not common in antivirals, which normally have isolated specific targets, inhibiting specific processes, such as virus entry into cells, synthesis of genetic material and of proteins, the assembly and release of new viral particles.

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