New therapeutic approach in fatty liver? | point of



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Platelets are involved in the development of fatty liver and liver cancer.

Unhealthy diet and lack of exercise: These two factors contribute significantly to the development of non-alcoholic fatty liver.

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Thurs 04 April 2019

The major risk factors for fatty liver are obesity and type 2 diabetes, caused by unfavorable eating habits and lack of exercise. But that is not all. Scientists at the German Cancer Research Center have found that platelets – called platelets – also play a role.

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In mice fed high fat, platelets are increasingly found in the liver. This has also been observed in people with non-alcoholic fatty liver disease, as the research team reports on Mathias Heikenwälder of the German Cancer Research Center. When the mice received anticoagulants, in addition to the high fat diet, which also acts on platelets, fewer of them were detectable in the liver and the number of inflammatory cells was smaller. Heikenwälder summarizes: "The rats were indeed overweight, but they had no fatty liver and no liver cancer."

In another pilot study, the scientists subsequently treated humans with a fatty liver with anticoagulants. As a result, they lost fat in the liver. Heikenwälder said, "If we can break the cycle of inflammatory processes, we can help those affected to reduce the risk of liver cancer induced by fatty liver."

Fatty non-alcoholic liver is on the rise, with about 30 to 40% of adults suffering from it. On the other hand, medications do not exist until now, only weight reduction and more exercise helps. A fatty liver can become inflamed, which promotes the development of liver cirrhosis and eventually liver cancer.

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