Ten pregnancies in a womb of a deceased donor were tried on 10 other occasions, but they were not reached or ended in miscarriage.
In the case of living donors, the success rate is higher. Up to 11 babies were born in the world thanks to a transplanted uterus. Sometimes the giver was the recipient's own mother.
It all happened in São Paulo, Brazil, between 2016 and 2017. The mother of the girl, who is 32 years old, was born without a uterus and received the womb of a woman in her 40s who was a mother three times and who died of an accident cerebral vascular disease.
The recipient suffered from Mayer-Rokitansky-Küster-Hauser syndrome, which affects approximately one in 4,500 women worldwide and does not cause the vagina, uterus, or uterus to form properly.
But her ovaries were in perfect condition so that the doctors could extract the eggs and fertilize them with the sperm of the future father. Then they froze.
At the time of the transplant, the expectant mother had to take medicines that weaken her immune system. In this way, he tried to prevent his body from rejecting the new uterus.
About six months after the transplant, the woman began to menstruate again. Soon after, they inserted the fertilized eggs and she became pregnant.
The pregnancy was a success and proceeded normally. Nine months later, on December 15, 2015, a 2.5 kg girl was born by cesarean section.
"The first live donor uterus transplants were a medical landmark and gave the possibility that infertile women could have a birth because of access to appropriate donors and necessary medical facilities," said Dr. Dani Ejzenberg of the Hospital das Clinicas, in Sao Paulo.
But he himself acknowledges that donors of a living uterus are rare and are usually close relatives or friends of the recipient, so the success of a pregnancy in the womb of a deceased donor is important.
Dr. Srdjan Saso of Imperial College London said the results are encouraging.
Source: BBC World